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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK20 All Species: 38.18
Human Site: Y181 Identified Species: 70
UniProt: Q8IZL9 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZL9 NP_001034892.1 346 38695 Y181 L L Y G A R Q Y D Q G V D L W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q5EDC3 243 27009 K105 P L A Q A Q V K S Y L Q M L L
Dog Lupus familis XP_533555 346 38425 Y181 L L Y G A R Q Y D Q G V D L W
Cat Felis silvestris
Mouse Mus musculus Q9JHU3 346 38361 Y181 L L Y G A R Q Y D Q G V D L W
Rat Rattus norvegicus Q4KM34 346 38431 Y181 L L Y G A R Q Y D Q G V D L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507089 345 38509 Y181 L L Y G A R Q Y D E G V D L W
Chicken Gallus gallus
Frog Xenopus laevis P20911 352 39672 Y196 L L F G A R M Y G V G V D M W
Zebra Danio Brachydanio rerio A8WIP6 344 39006 Y181 L L Y G A R K Y D E G V D L W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624845 304 34829 W167 S H Q I A T R W Y R A P E L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799108 346 39277 Y189 L L Y G A R K Y D E G A D L W
Poplar Tree Populus trichocarpa XP_002317890 416 47261 Y189 L L F G A K Q Y G A G V D V W
Maize Zea mays P23111 294 33816 R151 L A D F G L A R A F G I P V R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMT0 391 44511 Y187 L L F G A K Q Y G A A V D V W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 57.5 93.3 N.A. 94.2 93.6 N.A. 84.9 N.A. 39.4 75.4 N.A. N.A. 41.3 N.A. 69
Protein Similarity: 100 N.A. 60.6 97.1 N.A. 97.1 96.5 N.A. 93 N.A. 55.1 86.9 N.A. N.A. 60.9 N.A. 82.9
P-Site Identity: 100 N.A. 20 100 N.A. 100 100 N.A. 93.3 N.A. 66.6 86.6 N.A. N.A. 13.3 N.A. 80
P-Site Similarity: 100 N.A. 26.6 100 N.A. 100 100 N.A. 100 N.A. 80 100 N.A. N.A. 40 N.A. 93.3
Percent
Protein Identity: 40.1 38.1 N.A. 40.1 N.A. N.A.
Protein Similarity: 54.3 55.2 N.A. 54.9 N.A. N.A.
P-Site Identity: 66.6 13.3 N.A. 60 N.A. N.A.
P-Site Similarity: 86.6 26.6 N.A. 80 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 93 0 8 0 8 16 16 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 54 0 0 0 77 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 24 0 0 8 0 0 % E
% Phe: 0 0 24 8 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 77 8 0 0 0 24 0 77 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 16 16 8 0 0 0 0 0 0 0 % K
% Leu: 85 85 0 0 0 8 0 0 0 0 8 0 0 70 16 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 8 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % P
% Gln: 0 0 8 8 0 8 54 0 0 31 0 8 0 0 0 % Q
% Arg: 0 0 0 0 0 62 8 8 0 8 0 0 0 0 8 % R
% Ser: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 8 0 70 0 24 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 77 % W
% Tyr: 0 0 54 0 0 0 0 77 8 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _